By Barry J. Goldstein,Dirk Mueller-Wieland
By Barry J. Goldstein,Dirk Mueller-Wieland
By Jean V. Joseph,Hitendra R.H. Patel
By Adrian Chenzbraun
Echocardiography remains to be fairly underused within the administration of severely sick and hemodynamically volatile sufferers. there's a yes pattern for favoring echocardiography over invasive evaluation in in depth care devices, despite the fact that, transparent directions are missing. The author's event during the last few years reinforced the significance of a booklet masking this subject. the root for the construction this e-book was once the fruit of training classes and ward rounds in which the curiosity and receptiveness for this subject have been obvious.
By Yifrah Kaminer
This entire factor on Substance Abuse in adolescence starts off with articles on epidemiological tendencies, genetic danger elements, neurobiology of substance use problems, and race and gender institutions, after which presents unique experiences on prevention and numerous remedy methodologies. remedies mentioned comprise person and staff interventions (motivational interviewing and cognitive behavioral therapy), contingency reinforcement, multidimentional kinfolk treatment, pharmacotherapy, and post-treatment aftercare. additionally reviewed intimately are substance use problems and psychiatric comorbidity. the problem then takes an in depth examine rising components of shock in early life: playing and net profession, and effort drink use. by means of all bills, a must-read factor for psychiatrists everywhere.
By Jordi Rello,Marcos I. Restrepo
By Wolfgang Grisold,Riccardo Soffietti
Handbook of scientific Neurology: Neuro-Oncology, half I summarizes the current kingdom of clinical and medical wisdom within the box of neuro-oncology, together with info relating to diagnostic suggestions equivalent to imaging, besides immunology, molecular biology, and medical elements of tumors. administration and new healing options for tumors, together with gene remedy and molecularly precise remedies, also are covered.
Divided into 8 sections encompassing sixty one chapters, the booklet starts with an outline of the elemental rules of tumors, together with the epidemiology of fundamental imperative fearful approach tumors, angiogenesis and invasion in melanoma, the hyperlink among blood-brain barrier and mind edema, and the position of stem cells in gliomas. It proceeds with a dialogue of diagnostic instruments corresponding to neuroimaging, the foundations of tumor treatment corresponding to radiotherapy and immunotherapy, and medical trials in neuro-oncology. The reader is additionally brought to express tumor varieties resembling low-grade gliomas, anaplastic astrocytomas, and medulloblastoma and primitive neuroectodermal tumors, in addition to infrequent mind tumors like neurofibromatosis and different genetic syndromes. additionally, the ebook explains the neurological problems of systemic melanoma and issues from treatments.
This quantity will entice clinicians and neuroscientists in addition to researchers who are looking to achieve a greater realizing of the scientific positive factors and administration of the neurological manifestations of tumors.
By Antonio Bayés de Luna,Miquel Fiol-Sala MD,Elliot M. Antman MD
To facilitate right prognosis and advisor administration, the authors use a constant series to give an explanation for the ECG abnormalities for every website of coronary occlusion. A schematic of the coronary tree illustrates the purpose of occlusion.
the second one a part of the booklet encompasses a self-assessment part with a chain of 15 situations, every one of along with a number of 12-lead ECGs for research. those helpful examples assist you organize for on-the-spot interpretation within the emergency division or in depth care unit.
By David Snashall,Dipti Patel
By Mark R. Harrigan,John P. Deveikis,Agnieszka Ardelt
Neurointerventional radiology is evolving right into a rarified and complicated box, with extra buyers education to develop into neurointerventionalists than ever prior to. With those advancements comes a necessity for a unified instruction manual of concepts and crucial literature. In instruction manual of Cerebrovascular ailment and Neurointerventional method, Mark Harrigan and John Deveikis current the 1st sensible consultant to endovascular tools and supply a possible reference paintings for neurovascular anatomy and cerebrovascular illness from a neurointerventionalist’s point of view. This new gold-standard reference covers the elemental strategies and center philosophies of Neurointerventional radiology, whereas making a handbook that gives constitution and standardization to the sector. Authoritative and concise, instruction manual of Cerebrovascular ailment and Neurointerventional approach is the must-have paintings for today’s neurosurgeons, neuroradiologists, and interventional radiologists.
By Malcolm Brenner,Mien-Chie Hung
Provides professional, cutting-edge perception into the present growth of viral and non-viral gene therapy
Translational drugs has opened the gateway to the period of customized or precision medication. not a one-size-fits-all process, the remedy of melanoma is now in response to an realizing of underlying biologic mechanisms and is more and more being adapted to the molecular specificity of a tumor.
This e-book offers a complete assessment of the pertinent molecular discoveries within the melanoma box and explains how those are getting used for gene-based melanoma cures. Designed as a quantity within the Translational Oncology booklet sequence, Cancer Gene treatment by way of Viral and Non-viral Vectors bargains with the perform of gene-therapy, near to vectors for gene expression and gene move, in addition to viral treatment. It covers the heritage and present and destiny purposes of gene move in melanoma, and offers specialist perception at the development of viral and non-viral gene remedy with reference to supply procedure, vector layout, capability healing genes, and ideas and rules for melanoma gene therapy.
awarded in 3 components, Cancer Gene treatment via Viral and Non-viral Vectors covers:
• Translational melanoma study: Gene remedy via Viral and Non-viral Vectors
• Retroviruses for melanoma Therapy
• DNA Plasmids for Non-viral Gene treatment of Cancer
• Cancer remedy with RNAi introduced through Non-viral Membrane/Core Nanoparticles
• Cancer Gene remedy via Tissue-specific and Cancer-targeting Promptors
• MicroRNAs as medications and Drug ambitions in Cancer
Principles of scientific Trials in Gene Therapy
• Regulatory matters for brands of Viral Vectors and Vector-transduced Cells for section I/II Trials
• US rules Governing scientific Trials in Gene Therapy
• Remaining stumbling blocks to the good fortune of melanoma Gene Therapy
Focusing on rushing the method in medical melanoma care via bringing remedies as speedy as attainable from bench to bedside, Cancer Gene treatment by way of Viral and Non-viral Vectors is a fully important booklet for physicians, clinicians, researchers, and scholars serious about this quarter of medicine.